Category: Research and Science
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Argument against “DIY computational drug-discovery” trend in Bangladesh
I’m seeing a trend that bioscience students from Bangladesh (South Asia in general) are increasingly interested in publishing papers on computational drug design. Many bright students, undergrad or freshly graduated, are actually publishing drug designing related papers in good journals. I have also done similar projects. But now, I think it is a bad trend.…
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What is the alternative to the ‘junk DNA’ hypothesis?
After completing the human genome sequencing in the 2000s, much of our DNA, even more than half, was considered unnecessary. It was called “junk DNA,” “broken genes” trapped in the genome’s prison, and the DNA fossils of viruses that have been silenced. It was thought these destroyed DNA elements had no purpose and were unrelated…
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Clad-shift consistency of Dengue in Bangladesh
Last year I collaborated with cross-institution researchers from Bangladesh led by BCSIR on the severe Dengue outbreak in 2021. The study has been published in the BMC Virology Journal recently. Dengue remains a dangerous endemic disease causing many deaths and suffering in Bangladesh. My contribution was to analyze the phylodynamics of the Dengue virus (DENV).…
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The fascinating story of HIV origin
I have reviewed a paper by Sharp and Hahn (2011) in YouTube for my students in Evolution course (I am a TA for Spring 2020). This paper is a complete review on the fascinating origin of HIV and how AIDS becomes a pandemic.
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How to resolve conflict in Science: On FMDV classification problem
How a scholarly conflict on FMD virus classification between Bangladeshi and Chinese research-groups was resolved.
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How to use McFarland solution to visually compare bacterial culture
Say you have a bacterial isolate and you need to check its antibiotic resistance profile. In this case, you need to do an antibiogram study. Ideally, you’ll need to make bacterial lawn on Mueller-Hinton agar medium for doing antibiogram. For that purpose, you prepare bacterial culture from stock in nutrient broth and place it in…
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Achieving Expertise: How to Find the Elusive Origin of Replication Site in DNA?
This write-up was for a writing assignment in Coursera.com MOOC (Massive Open Online Course) , English Composition I: Achieving Expertise offerd from Duke University. There were four assignments, I submitted first two of them and later became very busy with my M.S. thesis work. The second assignment was to select a random picture and writing…